Ellagic Acid

rasberries

Time Course Production of Urolithins from Ellagic acid by Human Gut Microbiota

Garcia-Villalba and colleagues from CEBAS-CSIC (ES) have conducted a study using detailed experiments in vitro and in vivo to identify the intermediary and final catabolites of ellagic acid in the human gut in order to…read more

Interindividual variability in the human metabolism of ellagic acid: Contribution of Gordonibacter to urolithin production

Maria Romo-Vaquero and colleagues from the CEBAS-CSIC (ES) have examined the role of Gordonibacter and/or other human gut bacteria in human… read more

Bacchus-Biological significance of urolithins

Biological Significance of Urolithins, the Gut Microbial Ellagic Acid-Derived Metabolites: The Evidence So Far

Juan Carlos Espín and colleagues from CEBAS-CSIC (ES) have reviewed literature describing urolithin metabolites production by gut microbiota, their absorption, tissue distribution and pharmacokinetics, and… read more

bacchus other

Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health Status

Francesco Tomás-Barberán and colleagues from CEBAS-CSIC(ES) have described three phenotypes for urolithin production, after intake of ellagitannin and ellagic acid. The proposed phenotypes could explain inter-individual variability in… read more

Pom

Validated Method for the characterization and quantification of extractable and non-extractable ellagitannins after acid hydrolysis in pomegranate fruits, juices, and extracts

Rocio Garcia-Villalba and colleagues from CEBAS-CSIC (ES) have developed a new method for the analysis of the extractable and non-extractable ellagitannins, based on the quantification of acid hydrolysis products… read more

Pomegranate Image

Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients

Maria Nunez-Sanchez and colleagues from Quality, Safety and Bioactivity of Plant Foods (Campus de Espinardo, ES) and the Nutrition, Digestion, Surgery and Anatomical Pathology Services (Hospital Reina Sofia, Murcia, ES) found that colorectal cancer cells taken from patients who had consumed pomegranate extract (PE) contained bioactive polyphenols, such as ellagic acid (EA) and urolithins … read more